Phenotypes Associated with This Genotype

Genotype
MGI:2181881

• Allelic Composition: srt/srt
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:75360 )

• affected animals die shortly after birth

craniofacial

cleft secondary palate ( J:75360 )

growth/size/body

cleft secondary palate ( J:75360 )

decreased body length ( J:75360 )

• shortened body axis

respiratory system

respiratory failure ( J:75360 )

• likely leads to perinatal lethality

skeleton

absent proximal rib ( J:75360 )

• proximal portions of ribs are not present, causing a drastic size reduction of the chest

lordosis ( J:75360 )

• the lower cervical/upper thoracic region of the vertebral column are affected

abnormal vertebrae development ( J:75360 )

• abnormal ossification centers

digestive/alimentary system

cleft secondary palate ( J:75360 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
asphyxiating thoracic dystrophy		DOID:0050592	OMIM:PS208500	J:75360