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Phenotypes Associated with This Genotype
Genotype
MGI:2182592
Allelic
Composition		 Apctm1Tno/Apctm1Tno
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tno mutation (6 available); any Apc mutation (158 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased colon adenoma incidence ( J:43301 )
• colorectal adenomas observed when exon 14 was deleted by colorectal infection of an adenovirus exressing Cre recombinase

digestive/alimentary system
increased colon adenoma incidence ( J:43301 )
• colorectal adenomas observed when exon 14 was deleted by colorectal infection of an adenovirus exressing Cre recombinase

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
familial adenomatous polyposis DOID:0050424 OMIM:PS175100
 J:43301

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory