Phenotypes Associated with This Genotype

Genotype
MGI:2384058

• Allelic Composition: Jag1^tm1Grid/Jag1⁺
• Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal eye morphology ( J:54907 )

• Background Sensitivity: eye phenotypes are described as fully penetrant on an 80% C57BL/6 genetic background and incompletely penetrant on a mixed background

abnormal placement of pupils ( J:54907 )

irregularly shaped pupil ( J:54907 )

iris coloboma ( J:54907 )

• iris coloboma

cornea opacity ( J:54907 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Alagille syndrome	DOID:9245	OMIM:118450 OMIM:610205	J:54907