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Phenotypes Associated with This Genotype
Genotype
MGI:2446589
Allelic
Composition		 Abcd1tm1Kds/Y
Genetic
Background		 either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129/Sv * 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcd1tm1Kds mutation (0 available); any Abcd1 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Lipid clefts are seen in adrenocortical cells of Abcd1tm1Kds/Y mice

homeostasis/metabolism
abnormal lipid homeostasis ( J:42479 )
• storage of very long-chain fatty acids in the adrenal gland, brain, kidney, heart and liver
increased saturated fatty acids level ( J:42479 )
• storage of very long-chain fatty acids in the adrenal gland, brain, kidney, heart and liver

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
adrenoleukodystrophy DOID:10588 OMIM:300100
 J:42479

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory