Phenotypes Associated with This Genotype

Genotype
MGI:2449173

• Allelic Composition: Myo7a^sh1-6J/Myo7a^sh1-6J
• Genetic Background: involves: C57BLKS/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired swimming ( J:17340 )

• mice cannot swim

head tossing ( J:17340 )

• observed frequently

abnormal gait ( J:17340 )

• described as unsteady

retropulsion ( J:17340 )

• mice walk backwards on smooth surfaces, although not on pine shavings (cage material)

hearing/vestibular/ear

deafness ( J:17340 )

• mice are apparently deaf (details not given)

reproductive system

male infertility ( J:17340 )

♂ • affected males do not breed successfully

growth/size/body

decreased body size ( J:17340 )

• mice are smaller than littermates

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Usher syndrome type 1		DOID:0110826	OMIM:276900	J:17340