Phenotypes Associated with This Genotype

Genotype
MGI:2450518

• Allelic Composition: Hba^th-J/Hba⁺
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:32654 )

• fewer than expected heterozygous mice are found at weaning (39% compared to the expected 50%)

growth/size/body

decreased body weight ( J:45721 )

hematopoietic system

increased erythrocyte cell number ( J:45721 )

• erythrocytosis

decreased hemoglobin content ( J:45721 )

• low blood hemoglobin levels

microcytosis ( J:45721 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
alpha thalassemia		DOID:1099	OMIM:604131	J:32654 , J:45721