Phenotypes Associated with This Genotype

Genotype
MGI:2451169

• Allelic Composition: Sox9^tm2Crm/Sox9⁺; Tg(Col2a1-cre)1Bhr/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:79879 )

• 95% of animals die 10 days after birth; only a few survive and are able to mate

growth/size/body

disproportionate dwarf ( J:79879 )

skeleton

kyphosis ( J:79879 )

abnormal vertebrae morphology ( J:79879 )

• compression of cervical and thoracic verterbrae

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
campomelic dysplasia		DOID:0050463	OMIM:114290	J:79879