Phenotypes Associated with This Genotype

Genotype
MGI:2651886

• Allelic Composition: Nmf15/Nmf15⁺
• Genetic Background: C57BL/6J-Nmf15/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal pancreas morphology ( J:82238 )

enlarged pancreatic islets ( J:82238 )

• enlarged islets of Langerhans in the pancreas was noted in two animals

growth/size/body

increased body weight ( J:82238 )

obese ( J:82238 )

• mice are visibly obese by 12 weeks of age; in all litters +/- 50% of the mice exceeded the B6 female database mean weight by 2 S.D and +/- 25% of the mice exceeded the B6 male database mean weight by 2 S.D

liver/biliary system

hepatic steatosis ( J:82238 )

• mild fatty changes in liver were noted at 120 days of age; progressive with age up to 299-370 days of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
obesity		DOID:9970	OMIM:601665	J:82238