Phenotypes Associated with This Genotype

Genotype
MGI:2652741

• Allelic Composition: Gpx1^tm1Ysh/Gpx1⁺; Gpx2^tm2Coh/Gpx2^tm2Coh
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:71506 )

• 10% mortality before 35 days of age, however do not exhibit cachexia

digestive/alimentary system

perianal ulcer ( J:71506 )

• seen in 17% of mice

diarrhea ( J:71506 )

• seen in 17% of mice

intestinal inflammation ( J:71506 )

• seen in 50% of mice

immune system

intestinal inflammation ( J:71506 )

• seen in 50% of mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
inflammatory bowel disease		DOID:0050589	OMIM:PS266600	J:71506