Phenotypes Associated with This Genotype

Genotype
MGI:2653051

• Allelic Composition: Ndn^tm1Stw/Ndn⁺
• Genetic Background: involves: 129S1/Sv * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:57890 )

• Background Sensitivity: when chimeric males are bred with wild-type FVB females, lethality declines from 80% (on a C57BL/6 background) to 25% of mutant offspring, and males are more affected than females

respiratory system

respiratory distress ( J:57890 )

cellular

maternal imprinting ( J:57890 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Prader-Willi syndrome		DOID:11983	OMIM:176270	J:57890