Phenotypes Associated with This Genotype

Genotype
MGI:2653233

• Allelic Composition: Cryaa^Aey7/Cryaa^Aey7
• Genetic Background: C3HeB/FeJ-Cryaa^Aey7/Ieg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:72928 )

• clefts apparent in the subcortical zone and nucleus at 7 weeks of age; this region corresponded to regions of developing opacity; more severe than heterozygotes

cataract ( J:72928 )

• described as progressive, starting as a visible opacity in the embryonic nucleus and resulting in a zonal and nuclear opacity by 2 months of age; more severe than heterozygotes

microphthalmia ( J:72928 )

• small eyes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 9 multiple types		DOID:0110266	OMIM:604219	J:72928