Phenotypes Associated with This Genotype

Genotype
MGI:2654216

• Allelic Composition: Maf^Ofl/Maf⁺
• Genetic Background: either: 102/ElH or C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal pupillary reflex ( J:82475 )

• ona 102/ElH background, some pupils fail to dilate fully after atropine, suggesting abnormal development of the anterior segment

cataract ( J:82475 )

• described as pulverulent (powdery)

• Background Sensitivity: complete penetrance observed on a C3H/HeH background

• Background Sensitivity: incomplete penetrance and expressivity observed on a 102/ElH background

behavior/neurological

abnormal pupillary reflex ( J:82475 )

• ona 102/ElH background, some pupils fail to dilate fully after atropine, suggesting abnormal development of the anterior segment

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 21 multiple types		DOID:0110256	OMIM:610202	J:82475