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Phenotypes Associated with This Genotype
Genotype
MGI:2655512
Allelic
Composition
Hfetm1.1Nca/Hfetm1.1Nca
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hfetm1.1Nca mutation (1 available); any Hfe mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• Background Sensitivity: iron loading occurred more rapidly on a 129S6/SvEvTac background than on a mixed background
• less iron accumulation than in Hfetm2Nca homozygous mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hemochromatosis type 1 DOID:0111029 OMIM:235200
J:78536


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory