Phenotypes Associated with This Genotype

Genotype
MGI:2655649

hm1

• Allelic Composition: Atp6v0c^tm1Hka/Atp6v0c^tm1Hka
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:58416 )

• embryos die between E1.5 and E3.5

embryo

failure of zygotic cell division ( J:66430 )

• absence of discernible embryonic structures; embryos failed to differentiate into egg cylinders

abnormal embryonic tissue morphology ( J:66430 )

abnormal inner cell mass morphology ( J:66430 )

• disorganized cells of the ICM