Phenotypes Associated with This Genotype

Genotype
MGI:2657281

• Allelic Composition: Zic3^Bn/Zic3⁺
• Genetic Background: BNT/LeJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

situs ambiguus ( J:62608 )

♀ • abnormal organ position, found in more than 50% of Bn/Y males and 38% of carrier females

limbs/digits/tail

decreased caudal vertebrae number ( J:63168 )

♀ • fewer caudal vertebrae than normal

short tail ( J:13124 , J:14983 , J:63168 )

♀ • variable and milder severity compared to homozygous females and hemizygous males (J:13124)

♀ (J:14983)

♀ (J:63168)

kinked tail ( J:13124 , J:14983 , J:63168 )

♀ • one or more bends (J:13124)

♀ (J:14983)

♀ (J:63168)

skeleton

decreased caudal vertebrae number ( J:63168 )

♀ • fewer caudal vertebrae than normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:5776 , J:13124 , J:14983 , J:62608 , J:63168