Phenotypes Associated with This Genotype

Genotype
MGI:2658721

hm1

• Allelic Composition: Spi1^tm1Ram/Spi1^tm1Ram
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal eye development ( J:101493 )

• the pupillary membrane and tunica vasculosa lentis persist postnatally unlike in wild-type mice due to a defective clearance of apoptotic cells

persistence of hyaloid vascular system ( J:101493 )

hematopoietic system

decreased macrophage cell number ( J:101493 )

• mice lack ocular macrophages

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:95801 )

N • despite a lack of macrophages, wound healing occurs at the same rate as in wild-type mice

immune system

decreased macrophage cell number ( J:101493 )

• mice lack ocular macrophages