Phenotypes Associated with This Genotype

Genotype
MGI:2662011

• Allelic Composition: Ar^Tfm/Y; Insl3^tm1Imad/Insl3^tm1Imad
• Genetic Background: involves: 129/Sv * CD-1 * STOCK Eda^Ta

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal female reproductive system morphology ( J:83429 )

♀ • Mullerian duct derivatives were absent

abnormal gubernaculum morphology ( J:83429 )

♂ • there is no tight attachment of the testes to the inguinal region

abnormal male reproductive system morphology ( J:83429 )

♂

bilateral cryptorchism ( J:83429 )

♂ • bilateral cryptorchism with testes situated adjacent to the kidneys

♂ • lack of tight attachment to the inguinal region

♂ • testes were attached to the dorsal abdominal wall by well developed cranial suspsensory ligaments

absent epididymis ( J:83429 )

♂ • the epididymis was absent

absent vas deferens ( J:83429 )

♂ • the vas deferens was absent

abnormal secondary sex determination ( J:83429 )

♂

male pseudohermaphroditism ( J:83429 )

♂ • the male external and internal genitalia are not virilized

endocrine/exocrine glands

bilateral cryptorchism ( J:83429 )

♂ • bilateral cryptorchism with testes situated adjacent to the kidneys

♂ • lack of tight attachment to the inguinal region

♂ • testes were attached to the dorsal abdominal wall by well developed cranial suspsensory ligaments

skeleton

abnormal gubernaculum morphology ( J:83429 )

♂ • there is no tight attachment of the testes to the inguinal region

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cryptorchidism		DOID:11383	OMIM:219050	J:83429