Phenotypes Associated with This Genotype

Genotype
MGI:2662361

• Allelic Composition: Slit3^tm1.1Dor/Slit3^tm1.1Dor
• Genetic Background: involves: 129S1/Sv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:83292 )

• phenotype is stated to be identical to that of Slit3^tm1Dor homozygotes; however, no data are presented in J:83292

growth/size/body

decreased body weight ( J:83292 )

muscle

abnormal diaphragm morphology ( J:83292 )

diaphragmatic hernia ( J:83292 )

thin diaphragm muscle ( J:83292 )

liver/biliary system

herniated liver ( J:83292 )

digestive/alimentary system

herniated intestine ( J:83292 )

intestinal obstruction ( J:83292 )

respiratory system

lung hemorrhage ( J:83292 )

atelectasis ( J:83292 )

respiratory distress ( J:83292 )

cardiovascular system

lung hemorrhage ( J:83292 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital diaphragmatic hernia		DOID:3827	OMIM:142340 OMIM:222400 OMIM:610187	J:83292