reproductive system
• males exhbited a reduced distance
|
• arrested development
|
• though some follicles were observed in the early stages of antrum formation, most were arrested at the pre-antral phase
|
small ovary
(
J:5877
)
• arrested development
|
small testis
(
J:5877
)
• arrested development
|
cryptorchism
(
J:5877
)
• testes located in the abdomen
|
small uterus
(
J:5877
)
• arrested development
|
• failure of vagina to open fully
|
• rarely advanced beyond the diplotene stage
|
small penis
(
J:5877
)
|
• underdeveloped scrotum
|
endocrine/exocrine glands
• arrested development
|
• though some follicles were observed in the early stages of antrum formation, most were arrested at the pre-antral phase
|
small ovary
(
J:5877
)
• arrested development
|
small testis
(
J:5877
)
• arrested development
|
cryptorchism
(
J:5877
)
• testes located in the abdomen
|
growth/size/body
• male specific decrease in body weight evident at 6 weeks of age, putatively due to testosterone deficiency
|
nervous system
N |
• no abnormalities found
|
skeleton
N |
• no craniofacial abnormalities
|
homeostasis/metabolism
• reduced levels in the pituitary in both males and females
|
• reduced levels in the pituitary in both males and females
|
• reduced levels in both males and females
|
• reduced levels in the pituitary in both males and females
|
• reduced levels in the pituitary in both males and females
|
renal/urinary system
small penis
(
J:5877
)
|
digestive/alimentary system
• males exhbited a reduced distance
|
integument
cellular
• rarely advanced beyond the diplotene stage
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
hypogonadotropic hypogonadism 12 with or without anosmia | DOID:0090072 |
OMIM:614841 |
J:5877 |