Phenotypes for Pafah1b1 MGI:2664130 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Pafah1b1^tm2.2Awb/Pafah1b1⁺
Genetic Background	involves: 129S6/SvEvTac * NIH Black Swiss

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pafah1b1^tm2.2Awb mutation (0 available); any Pafah1b1 mutation (159 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

enlarged brain ventricles ( J:49531 )

abnormal hippocampus morphology ( J:49531 )

abnormal stratification in cerebral cortex ( J:49531 )

abnormal olfactory bulb morphology ( J:49531 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
lissencephaly	DOID:0050453	OMIM:PS607432	J:49531
Miller-Dieker lissencephaly syndrome	DOID:0060469	OMIM:247200	J:49531

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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