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Phenotypes Associated with This Genotype
Genotype
MGI:2664970
cx5
Allelic
Composition		 Fcgr1tm1Jsv/Fcgr1tm1Jsv
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Fcgr3tm1Jsv/Fcgr3tm1Jsv
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcgr1tm1Jsv mutation (4 available); any Fcgr1 mutation (36 available)
Fcgr2btm1Ttk mutation (7 available); any Fcgr2b mutation (48 available)
Fcgr3tm1Jsv mutation (5 available); any Fcgr3 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
impaired macrophage phagocytosis ( J:83995 )
• phagocytosis of all IgG-IC by macrophages is abrogated

hematopoietic system
impaired macrophage phagocytosis ( J:83995 )
• phagocytosis of all IgG-IC by macrophages is abrogated

cellular
impaired macrophage phagocytosis ( J:83995 )
• phagocytosis of all IgG-IC by macrophages is abrogated

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory