Phenotypes Associated with This Genotype

Genotype
MGI:2668440

• Allelic Composition: Grb10^{Gt(Betageo)1Ward}/Grb10^{Gt(Betageo)1Ward}
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

enlarged placenta ( J:84425 )

• the size of the placenta was also increased ~30% relative to wild-type

growth/size/body

increased birth body size ( J:84425 )

• neonates are ~30% larger than wild-type

increased fetal size ( J:84425 )

• embryonic overgrowth resulting in neonates that are ~30% larger than wild-type

enlarged liver ( J:84425 )

• disproportionate overgrowth of the liver

liver/biliary system

enlarged liver ( J:84425 )

• disproportionate overgrowth of the liver

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Silver-Russell syndrome	DOID:14681	OMIM:180860	J:84425