Phenotypes Associated with This Genotype

Genotype
MGI:2673459

• Allelic Composition: Fancd2^tm1Hou/Fancd2^tm1Hou
• Genetic Background: B6.129S4-Fancd2^tm1Hou

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:84892 )

• a significant deviation from expected Mendelian ratios was observed 5 days after birth on a C57BL/6J genetic background

• expected Mendelian ratios were observed 5 days after birth on a 129S4/SvJae genetic background

growth/size/body

decreased body weight ( J:84892 )

• observed on a C57Bl/6J genetic background but not on a 129S4/SvJae genetic background

postnatal growth retardation ( J:84892 )

• Background Sensitivity: observed on a C57Bl/6J genetic background but not on a 129S4/SvJae genetic background

fetal growth retardation ( J:84892 )

• reduced body size observed several days after birth indicated delayed development in utero

vision/eye

microphthalmia ( J:84892 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Fanconi anemia complementation group D2		DOID:0111083	OMIM:227646	J:84892