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Phenotypes Associated with This Genotype
Genotype
MGI:2677679
hm6
Allelic
Composition		 Lmx1btm1Rjo/Lmx1btm1Rjo
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmx1btm1Rjo mutation (0 available); any Lmx1b mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Podocyte abnormalities in Lmx1btm1Rjo/Lmx1btm1Rjo mice

renal/urinary system
abnormal podocyte morphology ( J:76089 )
• impaired differentiation
• retained cuboidal shape
abnormal podocyte foot process morphology ( J:76089 )
• reduced numbers of foot processes
absent podocyte slit diaphragm ( J:76089 )
• fail to form slit diaphragm

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory