Phenotypes Associated with This Genotype

Genotype
MGI:2679083

• Allelic Composition: Bmp4^tm3.1Blh/Bmp4^tm3.1Blh; Tg(Tnnt2-cre)5Blh/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality ( J:86001 )

cardiovascular system

cardiovascular system phenotype ( J:86001 )

N • no outflow tract abnormalities are seen

atrial septal defect ( J:86001 )

• atrial septal defect similar to that in mice heterozygous for Bmp4^tm1Blh and Bmp4^tm3.1Blh

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
atrioventricular septal defect		DOID:0050651	OMIM:606215 OMIM:614430 OMIM:614474	J:86001