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Phenotypes Associated with This Genotype
Genotype
MGI:2681612
hm1
Allelic
Composition
Fbxo32tm1Glas/Fbxo32tm1Glas
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo32tm1Glas mutation (0 available); any Fbxo32 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• upon sciatic nerve denervation, mice exhibit muscle atrophy at a reduced level compared to wild-type
• 56% muscle sparing was noted at 14 days post-denervation compared to wild-type mice
• mean muscle fiber size and fiber size variability remained similar to undenervated controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory