About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3033467
Allelic
Composition		 Hfetm2Sly/Hfetm3Sly
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hfetm2Sly mutation (0 available); any Hfe mutation (35 available)
Hfetm3Sly mutation (0 available); any Hfe mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased liver iron level ( J:88143 )
• increased hepatic iron concentrations in both males and females
• iron has a predominantly periportal distribution

liver/biliary system
increased liver iron level ( J:88143 )
• increased hepatic iron concentrations in both males and females
• iron has a predominantly periportal distribution

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
hemochromatosis type 1 DOID:0111029 OMIM:235200
 J:88143

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory