Phenotypes Associated with This Genotype

Genotype
MGI:3037429

cx4

• Allelic Composition: Csrp3^tm1Crni/Csrp3^tm1Crni; Tg(Myh6-ADRBK1)27Wjk/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:48062 , J:66250 )

N • partial rescue of the dilated cardiomyopathic phenotype observed in Csrp3^tm1Crni homozygotes, with some persistence of decreased contractility and fibrosis (J:48062)

N • no observed ventricular dilation (J:48062)

N • cellular and whole heart function is restored to normal (J:66250)

cardiac interstitial fibrosis ( J:48062 )

decreased heart ventricle muscle contractility ( J:48062 )

• relative to wild-type

• partial rescue of decreased contractility observed in Csrp3^tm1Crni homozygotes

muscle

decreased heart ventricle muscle contractility ( J:48062 )

• relative to wild-type

• partial rescue of decreased contractility observed in Csrp3^tm1Crni homozygotes

cellular

cardiac interstitial fibrosis ( J:48062 )