About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3038110
ot9
Allelic
Composition		 Gata1tm1Mym/Y
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm1Mym mutation (0 available); any Gata1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Gata1tm1Mym/Y embryos are smaller and anemic

mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:40321 )
• embryonic lethality is first detected at E11.5 and no live males seen by E12.5

hematopoietic system
abnormal embryonic erythropoiesis ( J:40321 )
• impaired primitive erythropoiesis
decreased erythroid progenitor cell number ( J:40321 )
• decrease in the number of erythroid cells and CFU-E in livers

embryo
absent vitelline blood vessels ( J:40321 )
• yolk sacs contain almost no blood vessels at E9.5
abnormal embryonic erythropoiesis ( J:40321 )
• impaired primitive erythropoiesis

growth/size/body
decreased embryo size ( J:40321 )

liver/biliary system

cardiovascular system
absent vitelline blood vessels ( J:40321 )
• yolk sacs contain almost no blood vessels at E9.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory