About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3039428
Allelic
Composition
Selltm1Flv/Selltm1Flv
Genetic
Background
involves: C57BL/6 * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Selltm1Flv mutation (0 available); any Sell mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• inflammation of the islet of Langerhans is seen by 9 weeks in mutant and wild-type mice

immune system
• inflammation of the islet of Langerhans is seen by 9 weeks in mutant and wild-type mice
• adoptive transfer experiment results with mutants backcrossed to NOD for 10 or more generations indicate that this reduction is a result of incomplete NOD genetic background
• the incidence of diabetes in these mutants is also decreased as a result of incomplete NOD genetic background

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
J:88974


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory