Phenotypes Associated with This Genotype

Genotype
MGI:3041561

• Allelic Composition: Ttn^mdm/Ttn^mdm
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:14016 )

• mice become very stiff and immobile and most are dead by 2 months of age

immune system

myositis ( J:14016 )

• acute and chronic myositis

muscle

myositis ( J:14016 )

• acute and chronic myositis

muscle degeneration ( J:14016 )

skeleton

kyphosis ( J:14016 )

• the entire thoracic and lumbar spine shows an exaggerated convex curvature by 12 days of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal recessive limb-girdle muscular dystrophy type 2J		DOID:0110283	OMIM:608807	J:74611