pigmentation
• coat color is indistinguishable from that of Tyrc homozygotes
(J:13058)
• the coat is entirely lacking pigment
(J:125080)
|
• eyes are pink and pigmentless
|
• little or no pigment in the iris
|
vision/eye
• eyes are pink and pigmentless
|
• little or no pigment in the iris
|
• eye size appears reduced compared to f Tyrc homozygotes
(J:13058)
• the eyes are only mildly reduced in size
(J:125080)
|
growth/size/body
• reduced body size compared to f Tyrc homozygotes
|
reproductive system
• litter size is reduced in homozygous female to homozygous male crosses
|
hearing/vestibular/ear
• no section of the cochlear duct was ever found to be normal
|
• abnormal in its entirety
|
• the majority of ears show dedifferentiation and cellular migrations in the cochlear duct and the saccule
|
nervous system
integument
• coat color is indistinguishable from that of Tyrc homozygotes
(J:13058)
• the coat is entirely lacking pigment
(J:125080)
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
ocular albinism with sensorineural deafness | DOID:0090100 | J:13058 | ||
Tietz syndrome | DOID:0090002 |
OMIM:103500 |
J:13058 | |
Waardenburg syndrome type 2A | DOID:0110950 |
OMIM:193510 |
J:13058 |