Phenotypes Associated with This Genotype

Genotype
MGI:3044414

• Allelic Composition: Mitf^Mi-wh/Mitf⁺
• Genetic Background: involves: C57BL * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mitf^Mi-wh/+

pigmentation

diluted coat color ( J:13058 , J:125080 )

• coat color is gray and somewhat lighter than that of Myo5a^d homozygotes (J:13058)

• coat color darkens slightly with age (J:13058)

white spotting ( J:125080 )

• small spots may occur on the back, but spotting is not found on the head

abnormal foot pigmentation ( J:13058 )

• reduced foot pigmentation

decreased tail pigmentation ( J:13058 )

• reduced tail pigmentation

abnormal iris pigmentation ( J:125080 )

• moderate dilution of the iris pigmentation

decreased eye pigmentation ( J:13058 )

• eyes are a very dark ruby color

limbs/digits/tail

decreased tail pigmentation ( J:13058 )

• reduced tail pigmentation

vision/eye

abnormal iris pigmentation ( J:125080 )

• moderate dilution of the iris pigmentation

decreased eye pigmentation ( J:13058 )

• eyes are a very dark ruby color

integument

diluted coat color ( J:13058 , J:125080 )

• coat color is gray and somewhat lighter than that of Myo5a^d homozygotes (J:13058)

• coat color darkens slightly with age (J:13058)

white spotting ( J:125080 )

• small spots may occur on the back, but spotting is not found on the head

abnormal foot pigmentation ( J:13058 )

• reduced foot pigmentation

decreased tail pigmentation ( J:13058 )

• reduced tail pigmentation

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
ocular albinism with sensorineural deafness		DOID:0090100		J:13058
Tietz syndrome		DOID:0090002	OMIM:103500	J:13058
Waardenburg syndrome type 2A		DOID:0110950	OMIM:193510	J:13058