Phenotypes Associated with This Genotype

Genotype
MGI:3045805

cx1

• Allelic Composition: Igh-J^tm1Dhu/Igh-J^{tm1(VDJ-17.2.25)Wabl}; Igk^tm1Dhu/Igk^tm1Dhu
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal B cell differentiation ( J:33628 )

• precursor B cells and B lymphocytes are reduced by 1/3 to 1/2

abnormal immature B cell morphology ( J:89757 )

• 80% of bone marrow B cells have an immature phenotype

• rapid turnover

immune system

abnormal B cell differentiation ( J:33628 )

• precursor B cells and B lymphocytes are reduced by 1/3 to 1/2

abnormal immature B cell morphology ( J:89757 )

• 80% of bone marrow B cells have an immature phenotype

• rapid turnover