Phenotypes Associated with This Genotype

Genotype
MGI:3047131

• Allelic Composition: Fanca^tm1Wong/Fanca^tm1Wong
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal cranium morphology ( J:85108 )

endocrine/exocrine glands

small testis ( J:85108 )

♂

growth/size/body

decreased body weight ( J:85108 )

• Background Sensitivity: observed on a C57BL/6 genetic background

postnatal growth retardation ( J:85108 )

• observed on a C57BL/6 genetic background

reproductive system

decreased germ cell number ( J:85108 )

• Background Sensitivity: observed in both 129S6/SvEvTac and C57BL/6 genetic backgrounds, however a more severe depletion was observed in the C57BL/6 background

small testis ( J:85108 )

♂

skeleton

abnormal cranium morphology ( J:85108 )

vision/eye

microphthalmia ( J:85108 )

• often observed in conjunction with craniofacial abnormalities

• Background Sensitivity: exhibited on a C57BL/6 genetic background

cellular

decreased germ cell number ( J:85108 )

• Background Sensitivity: observed in both 129S6/SvEvTac and C57BL/6 genetic backgrounds, however a more severe depletion was observed in the C57BL/6 background

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Fanconi anemia complementation group A		DOID:0111095	OMIM:227650	J:85108