Phenotypes Associated with This Genotype

Genotype
MGI:3047777

• Allelic Composition: Avpr2^tm1Jwe/Avpr2⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CF-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

polydipsia ( J:66094 )

♀ • mice drank about two times more water than controls

homeostasis/metabolism

decreased urine osmolality ( J:66094 )

♀ • urine hypoosmolality

renal/urinary system

decreased urine osmolality ( J:66094 )

♀ • urine hypoosmolality

abnormal kidney physiology ( J:66094 )

♀ • reduced urine concentrating ability

polyuria ( J:66094 )

♀ • mice produced about three times more urine than controls

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
nephrogenic diabetes insipidus		DOID:12387		J:66094