Phenotypes for Hoxb1 Tfap2a MGI:3050415 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Hoxb1^tm5Mrc/Hoxb1^tm7Mrc Tfap2a^tm1(cre)Moon/Tfap2a⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxb1^tm5Mrc mutation (0 available); any Hoxb1 mutation (24 available)
Hoxb1^tm7Mrc mutation (0 available); any Hoxb1 mutation (24 available)
Tfap2a^tm1(cre)Moon mutation (1 available); any Tfap2a mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:91364 )

N	• no behavioral abnormalities are seen

nervous system

decreased motor neuron number ( J:91364 )

• the average number of motor neurons is significantly reduced in mutants compared to wild-type mice although not to the same extent as in compound heterozygous mutants carrying Tg(Wnt1-cre)11Rth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24