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Phenotypes Associated with This Genotype
Genotype
MGI:3054096
cx6
Allelic
Composition		 Cdk2tm1Sgo/Cdk2tm1Sgo
Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk2tm1Sgo mutation (1 available); any Cdk2 mutation (18 available)
Cdk6tm1Bbd mutation (1 available); any Cdk6 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal oogenesis ( J:92529 )
• marked defects in oogenesis seen
abnormal spermatogenesis ( J:92529 )
• marked defects in spermatogenesis seen
infertility ( J:92529 )
• double homozygotes are sterile

cellular
abnormal oogenesis ( J:92529 )
• marked defects in oogenesis seen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory