Analysis Tools
mortality/aging
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• unlike mice that do not carry Casp8tm1.1Yuan, compound heterozygous mutants survive injection with an anti-Fas Ab
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hematopoietic system
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• 2 days after induction of cre expression the ability of progenitor cells to form myeloid or B lymphoid colonies in culture or in transplant studies is significantly decreased
• the ability of these progenitors to differentiate into macrophages is also decreased after induction of cre expression
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