Analysis Tools
mortality/aging
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• increased sensitivity to LPS and TNF induced-lethality are seen
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• homozygotes begin to die after 1 week of age
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digestive/alimentary system
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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growth/size/body
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• homozygotes are runted by 1 week of age
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hematopoietic system
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• increased numbers of activated granulocytes are seen in spleens and livers
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• increased numbers of activated lymphocytes are seen in spleens and livers
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• increased numbers of activated granulocytes are seen in spleens and livers
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immune system
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• increased numbers of activated granulocytes are seen in spleens and livers
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• increased numbers of activated lymphocytes are seen in spleens and livers
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• increased numbers of activated granulocytes are seen in spleens and livers
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• severe bone marrow inflammation and tissue damage are seen at 3 to 6 weeks of age
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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renal/urinary system
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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skeleton
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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liver/biliary system
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• severe inflammation and tissue damage are seen at 3 to 6 weeks of age
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integument
