Phenotypes Associated with This Genotype

Genotype
MGI:3512004

• Allelic Composition: Ddb2^tm1Pra/Ddb2^tm1Pra
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:95633 )

• 100% died between 20 and 26 months of age

neoplasm

increased tumor incidence ( J:95633 )

• broad spectrum of tumors found in mice dying between 20 and 26 months of age

• high susceptibility to UV induced tumor incidence

• develop very aggressive tumors, death occurs within 3 weeks of tumor development

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
xeroderma pigmentosum group E		DOID:0110846	OMIM:278740	J:95633