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Phenotypes Associated with This Genotype
Genotype
MGI:3512005
Allelic
Composition
Ddb2tm1Pra/Ddb2+
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddb2tm1Pra mutation (1 available); any Ddb2 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 70% (7 of 10) died between 20 and 26 months of age

neoplasm
• broad spectrum of tumors found in mice dying between 20 and 26 months of age
• 3 of 7 dead mice had tumors of varying types

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
xeroderma pigmentosum group E DOID:0110846 OMIM:278740
J:95633


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory