Phenotypes for Fgf23 Phex MGI:3512461 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Fgf23^tm1Blan/Fgf23⁺ Phex^Hyp/Y
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf23^tm1Blan mutation (0 available); any Fgf23 mutation (18 available)
Phex^Hyp mutation (2 available); any Phex mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

increased diameter of femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

skeleton

short femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

increased diameter of femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

abnormal long bone metaphysis morphology ( J:94041 )

• exhibited cupping of the metaphysis below the growth plates

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
X-linked dominant hypophosphatemic rickets		DOID:0050445	OMIM:307800	J:94041

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24