Phenotypes for Fgf23 Phex MGI:3512461 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fgf23^tm1Blan/Fgf23⁺ Phex^Hyp/Y
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf23^tm1Blan mutation (0 available); any Fgf23 mutation (18 available)
Phex^Hyp mutation (2 available); any Phex mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

increased diameter of femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

skeleton

short femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

increased diameter of femur ( J:94041 )

• extremely short and thickened femurs similar to Phex^Hyp hemizygotes

abnormal long bone metaphysis morphology ( J:94041 )

• exhibited cupping of the metaphysis below the growth plates

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
X-linked dominant hypophosphatemic rickets		DOID:0050445	OMIM:307800	J:94041

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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