Phenotypes for Cnga3 Rpe65 MGI:3521968 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cnga3^tm1Biel/Cnga3^tm1Biel Rpe65^tm1Tmr/Rpe65^tm1Tmr
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga3^tm1Biel mutation (0 available); any Cnga3 mutation (27 available)
Rpe65^tm1Tmr mutation (1 available); any Rpe65 mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal eye electrophysiology ( J:71529 )

• at stimuli ranging from 0.0001 to 25 cds/m2, scotopic single-flash ERGs of double homozygotes are almost identical to those of Rpe65^tm1Tmr single mutants, indicating that rods are responsible for the light responses in Rpe65^tm1Tmr mutants

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Leber congenital amaurosis 2		DOID:0110016	OMIM:204100	J:71529

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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