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Phenotypes Associated with This Genotype
Genotype
MGI:3525175
cn3
Allelic
Composition		 Psen1tm2Shn/Psen1tm2Shn
Psen2tm1Haa/Psen2+
Tg(Msx2-cre)5Rem/0
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psen1tm2Shn mutation (1 available); any Psen1 mutation (61 available)
Psen2tm1Haa mutation (0 available); any Psen2 mutation (32 available)
Tg(Msx2-cre)5Rem mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal hair follicle morphology ( J:94517 )
• showed a transient phenotype in embryo-deleted skin but developed a normal coat by P22 with a few abnormal looking follicles

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory