Phenotypes Associated with This Genotype

Genotype
MGI:3526244

ht2

• Allelic Composition: Bmpr2^tm1Kmi/Bmpr2⁺
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal sternocostal joint morphology ( J:95124 )

• eight ribs, instead of nine, were attached to the sternum

vertebral transformation ( J:95124 )

• exhibited alleviated vertebral defects compared to homozygous Acvr2b mutants

• transformation of the 23rd vertebra to the 16th thoracic vertebra (as seen in homozygous Acvr2b mutants) was incomplete

• vertebra 29 of most mutants was transformed to the first sacral vertebra instead to the 6th lumbar vertebra (as seen in homozygous Acvr2b mutants)