Phenotypes for Myo6 Myo15a MGI:3528187 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Myo15a^sh2/Myo15a^sh2 Myo6^sv/Myo6^sv
Genetic Background	involves: B10.HA/(33NX)Sn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo15a^sh2 mutation (1 available); any Myo15a mutation (136 available)
Myo6^sv mutation (1 available); any Myo6 mutation (91 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:86379 )

• slightly reduced body size

hearing/vestibular/ear

abnormal organ of Corti morphology ( J:86379 )

abnormal cochlear hair cell stereociliary bundle morphology ( J:86379 )

• at 3-4 weeks of age, a few short stereocilia protrude from each hair cell in addition to a single giant stereocilium

short cochlear hair cell stereocilia ( J:86379 )

nervous system

abnormal cochlear hair cell stereociliary bundle morphology ( J:86379 )

• at 3-4 weeks of age, a few short stereocilia protrude from each hair cell in addition to a single giant stereocilium

short cochlear hair cell stereocilia ( J:86379 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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