About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3528980
Allelic
Composition
Notch3tm1Ul/Notch3tm1Ul
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch3tm1Ul mutation (0 available); any Notch3 mutation (94 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• vascular smooth muscle is normal in the thoracic aorta and common carotid arteries and light and electron microscopic examination detected no abnormalities in the thoracic and abdominal aortas or the carotid, leptomeningeal, and cerebral cortical penetrating arteries

normal phenotype
• homozygotes are viable with normal growth, reproduction, and morphology of the brain, heart, lung, eye, and skin

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT CADASIL 1 DOID:0111035 OMIM:125310
J:95927


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory