Analysis Tools
neoplasm
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• detected well-differentiated adenocarcinoma (prostate cancer) from 10 weeks of age and demonstrated a steadily prolonged cancer development, with a majority of well and moderately differentiated adenocarcinomas in almost all age groups
• starting from age of 52 weeks, all mutant mice synchronously developed visible cancer and after 90 weeks, a few mice developed large tumor with endoneurocrine cancinoma tumor foci characterized
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• developed prostatic intraepithelial neoplasia immediately after puberty and saw prostatic intraepithelial neoplasia with microinvasion at 6-7 weeks in 69.9% of mutants
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• by age of 70 weeks and over, metastases to outside prostate organ to liver and lung were found in several mutants
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endocrine/exocrine glands
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• enlarged dorsolateral prostate lobes at 52 weeks of age
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• enlarged ventral prostate lobes at 52 weeks of age
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• detected well-differentiated adenocarcinoma (prostate cancer) from 10 weeks of age and demonstrated a steadily prolonged cancer development, with a majority of well and moderately differentiated adenocarcinomas in almost all age groups
• starting from age of 52 weeks, all mutant mice synchronously developed visible cancer and after 90 weeks, a few mice developed large tumor with endoneurocrine cancinoma tumor foci characterized
|
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• developed prostatic intraepithelial neoplasia immediately after puberty and saw prostatic intraepithelial neoplasia with microinvasion at 6-7 weeks in 69.9% of mutants
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immune system
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• by 60 weeks of age, pelvic lymph nodes appeared as visible, enlarged glands
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reproductive system
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• enlarged dorsolateral prostate lobes at 52 weeks of age
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• enlarged ventral prostate lobes at 52 weeks of age
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|
• detected well-differentiated adenocarcinoma (prostate cancer) from 10 weeks of age and demonstrated a steadily prolonged cancer development, with a majority of well and moderately differentiated adenocarcinomas in almost all age groups
• starting from age of 52 weeks, all mutant mice synchronously developed visible cancer and after 90 weeks, a few mice developed large tumor with endoneurocrine cancinoma tumor foci characterized
|
|
|
• developed prostatic intraepithelial neoplasia immediately after puberty and saw prostatic intraepithelial neoplasia with microinvasion at 6-7 weeks in 69.9% of mutants
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| prostate cancer | DOID:10283 |
OMIM:176807 OMIM:300147 OMIM:300704 OMIM:601518 OMIM:602759 OMIM:608656 OMIM:608658 OMIM:609299 OMIM:609558 OMIM:610321 OMIM:610997 OMIM:611100 OMIM:611868 OMIM:611928 OMIM:611955 OMIM:611958 OMIM:611959 |
J:96884 | |
