Phenotypes Associated with This Genotype

Genotype
MGI:3574666

• Allelic Composition: Enam^Rgsc514/Enam⁺
• Genetic Background: involves: C57BL/6JJcl * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal tooth morphology ( J:96349 )

• a gap is seen between the enamel and the dentin core

abnormal enamel morphology ( J:96349 )

• enamel surface of the molars appears rough with microscopic cracks and delamination; however, the enamel is of normal thickness

• similar but more prominent enamel defects are seen on the incisors

growth/size/body

abnormal tooth morphology ( J:96349 )

• a gap is seen between the enamel and the dentin core

abnormal enamel morphology ( J:96349 )

• enamel surface of the molars appears rough with microscopic cracks and delamination; however, the enamel is of normal thickness

• similar but more prominent enamel defects are seen on the incisors

skeleton

abnormal tooth morphology ( J:96349 )

• a gap is seen between the enamel and the dentin core

abnormal enamel morphology ( J:96349 )

• enamel surface of the molars appears rough with microscopic cracks and delamination; however, the enamel is of normal thickness

• similar but more prominent enamel defects are seen on the incisors

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
amelogenesis imperfecta type 1B		DOID:0110052	OMIM:104500	J:96349